In the showdown between the Premier League's best two teams, Liverpool manager Jurgen Klopp opted to start with the quartet of in-form Diogo Jota, Roberto Firmino, Mohamed Salah and Sadio Mane.
It was the first time Klopp had played all four together and it caused problems for City early on.
After the international break, City face another of their top-six rivals in Spurs.
And Mourinho can boast a top-quality attacking line-up with Harry Kane, Heung-min Son and Gareth Bale.
Jose Mourinho is hunting another Premier League title (Image: GETTY)
Carlos Vinicius, Lucas Moura and Steven Bergwijn are also available to Mourinho and former City midfielder Michael Brown thinks the Spurs manager would be wise to emulate Klopp.
“I think it’s great, it’s an unbelievable front three," he told Football Insider.
"We had the same discussions with Liverpool about their front three, they managed to squeeze four in.
“Will Mourinho squeeze more in? It’s great, Gareth Bale, once he’s fit, will be a brilliant player that we all know how well he can do in the Premier League.
Harry Kane and Heung-min Son have starred for Spurs this season (Image: GETTY)
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“If you ask me if they’ll all be first choice against Manchester City, I’m sure he’ll try and get as many in as he possibly can.
"Then it’s the European fixtures after that where he can rotate.”
Meanwhile, Harry Kane has claimed Dele Alli's omission from the England squad is a sign of the strength in depth available at international level.
Alli has lost his place at club and international level after an alarming dip in form and as it stands is unlikely to be in the England squad for the European Championships next summer.
And Kane says reputation means nothing with so many young stars emerging.
“I think it just shows the strength in the youth players.
“Maybe younger players are starting to get their chance a bit earlier now.
“That’s the thing with England, there’s always another great player in your position so you always have to make sure you’re working hard and make sure you’re improving, no matter how many goals or caps you have.”
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