Manchester City manager Pep Guardiola will be forced to utilise his squad depth against West Ham after a string of injuries has made team selection difficult.
However, a gruelling 120 minutes at Wembley means several players are in need of a rest while Fernandinho and Aymeric Laporte are the latest stars to be sidelined through injury.
Laporte was replaced by Vincent Kompany at half-time of the win over Chelsea while Fernandinho limped off in the closing stages of extra time.
Both are expected to be out for several weeks, placing a huge strain on Guardiola’s squad as they look to complete the quadruple.
John Stones and Benjamin Mendy are also still on the treatment table so City find themselves short of options in defence.
Nicolas Otamendi is likely to partner Kompany at centre-back while Danilo and Oleksandr Zinchenko are options at left-back.
Ilkay Gundogan should deputise for Fernandinho in front of the back four while Kevin De Bruyne, David Silva and Bernardo Silva are all options in the midfield trio.
Man City team news: Fernandinho is ruled out of the upcoming clash with West Ham (Image: buildlineup.com•GETTY)
Man City team news: The Brazilian suffered an injury in the Carabao Cup final against Chelsea (Image: GETTY)
Bernardo played the whole match against Chelsea in an advanced role and is most likely to be rested if Riyad Mahrez is recalled on the right flank.
In attack, Sergio Aguero is almost certain to start in attack with Gabriel Jesus still an injury doubt.
City are currently a point behind Liverpool in the Premier Legaue but hold a far superior goal difference with 11 matches remaining in the campaign.
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Man City team news: Is this how Pep Guardiola's side will line up against West Ham? (Image: buildlineup.com)
Manchester City predicted line-up vs West Ham United – Premier League
(4-3-3): Ederson; Walker, Kompany, Otamendi, Zinchenko; Gundogan, De Bruyne, D. Silva; Mahrez, Sane, Aguero