Should Chelsea win, Leicester are likely to be crowned champions before 10pm - although Foxes boss Claudio Ranieri will be the last to know as he flies back from Italy after a day trip to take his his 96-year-old mother out for lunch.
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Tottenham and Chelsea drew 0-0 when the two teams met last in November
Gary Cahill is also expected to come back into the home side's defence, despite missing last week's win over Bournemouth through illness.
Spurs midfielder Dele Alli begins his three-match ban for violent conduct, Eric Dier is doubtful after suffering concussion against West Brom but Nabil Bentaleb is out with a knee injury.
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