The France international has been one of Chelsea’s most important players since he joined the club in 2016.
Manager Maurizio Sarri is also sweating over the fitness of trusted midfielder Jorginho, who also suffered a knock in training last week.
Chelsea are already without Callum Hudson-Odoi and Ruben Loftus-Cheek after they both ruptured their Achilles tendons.
Stalwart central defender Antonio Rudiger is also out after picking up a knee injury which requires surgery.
N'Golo Kante is an injury doubt for Chelsea's clash with Arsenal (Image: GETTY )
Chelsea suffer HUGE injury blow ahead of Europa League final with Arsenal (Image: GETTY )
Sarri, whose future at Chelsea is unstable following rumours that the Italian will be replaced by Frank Lampard once the season is up, spoke about Chelsea’s season in a news conference earlier this week.
"I think we had a good season, with a lot of problems of course," he said.
"We lost two, three games very badly, but we finished third, we got to the League Cup final, a very difficult competition.
“Now we have the opportunity to play the Europa League final.
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Arsenal players train for Europa League final against Chelsea