The Togo striker has returned from compassionate leave but is not yet fully fit, so is unlikely to start.
Mauricio Pochettino has an otherwise fully-fit squad for the match.
However, Burnley's trip to White Hart Lane is likely to come too soon for Sam Vokes, although the striker is nearing a first-team return.
The Wales international is instead expected to play for the Clarets' development squad on Monday against Blackpool.
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Emmanuel Adebayor returns in time for Tottenham's clash with Burnley
Full-back Ben Mee has fully recovered from the illness which forced him off against Southampton, but Michael Duff (calf) has suffered a setback and joins Matt Taylor (Achilles) and Stephen Ward (ankle) on the sidelines.
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