Daley Blind is a doubt for the game against England
Jasper Cillessen has definitely been ruled out after breaking his nose in training and will be replaced by Tottenham No2 Michel Vorm.
And Chelsea midfielder Marko van Ginkel has also been given the nod following a knee injury to Ajax captain Davy Klaassen.
Manchester United's Blind is also a doubt after he was forced to sit out training with a minor hamstring injury.
"My hamstring is stiff," he told Dutch newspaper De Telegraaf.
Daley Blind Player Profile
"I didn't want to take any risks in view of the upcoming games. We have to see how it goes.
I didn't want to take any risks in view of the upcoming games
Daley Blind
Invalid email
We use your sign-up to provide content in ways you've consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. Read our Privacy Policy
"But I don't think it's that bad."
United return to action after the international break on Sunday, hosting Everton at Old Trafford (4pm).
Michel Vorm en Marco van Ginkel vervangen Jasper Cillessen (gebroken neus) en Davy Klaassen (knie) voor #ENGNED. pic.twitter.com/kzqyxUOvZf