Frank Lampard (left) and Branislav Ivanovic will be out of action for a month [GETTY]
Ivanovic was forced off with a knee injury, while Lampard sustained a muscle injury in the 2-1 win over Liverpool and Mourinho initially expected a quick return from both.
Chelsea coped well without the pair, seeing off Southampton in what seemed a routine 3-0 victory.
In his post-match interview, Mourinho admitted the Christmas period was tough, what with the toll that suspensions and injuries took but he was proud with the way his side acquitted themselves.
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Jose Mourinho has had to rotate a squad hit by suspensions and injuries [GETTY]
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"This period is difficult for everyone, and in our case it was very difficult because we played Arsenal, Liverpool and then Southampton away," he told the club's official website.
"We always had suspensions and injuries, so the squad was brilliant in the way they answered to our needs."
Chelsea switch their attentions to the FA Cup this weekend, when they take on Derby.
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