Pep Guardiola is facing somewhat of a selection headache, due to the multiple injuries plaguing his squad.
Ederson, Rodri, David Silva and Aymeric Laporte will all be out for the Citizens, while Leroy Sane is also set to miss out.
Due to their absentees, they are expected to take a much more defensive attitude tomorrow afternoon.
But Nicol believes Liverpool will go for it from the first minute, while City will have no choice but to be much more defensive and tight in their approach.
Aymeric Laporte is still out through injury (Image: GETTY)
“Liverpool will go for this, 100-per-cent,” he said on ESPN FC.
“I think City will do what they did last year and be a little bit cautious.
“With the back-line they have, they can’t go to Anfield and say ‘let’s open this game up and see who wins’, because there’ll only be one winner.
“If they leave holes, Liverpool will kill them going forward.
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Liverpool are still unbeaten at the top of the league (Image: GETTY)
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“So Manchester City will have to be a little bit deeper and a little bit tighter.
“Regardless of the score, Liverpool will play their game and go after it.
Liverpool vs Manchester City kicks off at 4pm tomorrow.