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Man Utd vs Chelsea: Premier League match preview
New Manchester United star Harry Maguire is in line to make his debut after signing from Leicester for a world-record fee for a defender.
Midfielder Paul Pogba is also in contention following a back injury, but Alexis Sanchez is unlikely to feature following his involvement in the Copa America this summer.
Chelsea could be without N'Golo Kante, who is a doubt with the knee injury that disrupted his pre-season.
Ruben Loftus-Cheek, Antonio Rudiger and Callum Hudson-Odoi all remain sidelined for the Blues.
Manchester United boss Ole Gunnar Solskjaer: "I'm very confident that we'll get goals from (Anthony) Martial, Daniel James, (Marcus) Rashford and Jesse Lingard.
"I believe Mason Greenwood is going to be playing and involved a lot and, when he is, he's going to score goals."
Chelsea manager Frank Lampard: "We have to remain competitive while we are in this position.
"With the ban it has been easy to write off this squad, and I don't write off this squad at all.
Man Utd vs Chelsea: Find out how to watch the match (Image: GETTY)
"I think that what is important is that you have a target within the group. What matters is how we approach things. We will see how we go."
Live television coverage can be found on Sky Sports Main Event.
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Man Utd vs Chelsea: Who will come out on top? (Image: GETTY)
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Man Utd: Solskjaer jokes he's happy Lampard isn't playing
You can also watch the game on NOW TV - for more information on how to subscribe, click here.
Build-up coverage gets underway following the conclusion of Newcastle vs Arsenal.
Can I live stream Man Utd vs Chelsea?
Streaming is available through the Sky Go app for existing customers.
This can be done through a range of mobile devices, tablets, computers and games consoles.