“He decided on not continuing. Hopefully it will not be a big issue. We will see tomorrow, maybe the day after tomorrow.”
Aguero is not expected to be on the sidelines for long, although he may not be risked for the visit of Cardiff.
Gabriel Jesus is a natural replacement for the City talisman, while it remains to be seen who will play in support of the Brazilian.
Bernardo Silva and Raheem Sterling started out wide against Fulham, with the former scoring the opening goal against the relegation-threatened outfit.
Man City team news: Sergio Aguero is an injury doubt ahead of the clash with Cardiff (Image: buildlineup.com•GETTY)
Man City: Games coming 'thick and fast' for Guardiola says pundit
Sterling was below-par at Craven Cottage and Guardiola must decide whether to rotate the England winger in favour of Leroy Sane or Riyad Mahrez.
Sane is most likely to come in, having not been used against Fulham while Mahrez played just two minutes in the comfortable victory.
John Stones could return at the expense of Nicolas Otamendi after being named in the matchday squad last time out while Oleksandr Zinchenko should continue at left-back.
Finally, Fernandinho made his return from injury against Fulham and is expected to start while Bernardo, David Silva, Kevin De Bruyne and Ilkay Gundogan will compete for the other midfield spots.
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Man City team news: Is this how Pep Guardiola's side will line up against Cardiff? (Image: buildlineup.com)
Manchester City predicted line-up vs Cardiff City – Premier League
(4-3-3): Emerson; Walker, Stones, Laporte, Zinchenko; Fernandinho, B. Silva, De Bruyne; Sterling, Sane, Jesus