England boss Gareth Southgate has until June 4 to name his 23-man squad for the World Cup.
Southgate is expected to finalise his plans when the Premier League season ends on May 13.
He is hoping to announce his party for the trip to Russia before the friendly against Nigeria on June 2.
Writing on Twitter, one fan said: “Oxlade looks to be heading for at least a few months on the sidelines. If those scenes and history is anything to go by, he will miss the World Cup.
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Alex Oxlade-Chamberlain was taken off on a stretcher
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“He still has not put together a full season. Get well soon.”
Another added: “Oxlade was starting to look like a decent player for Liverpool, hope the injury ain’t that bad
While an Arsenal supporter said: “I’m genuinely gutted for Oxlade Chamberlain.
“Hope it’s nothing serious and that he is back for the Champions League final if Liverpool get to it and for the World Cup.
“Not for Liverpool’s sake, but for his, genuinely think he’s a great guy.”