The 23-year-old was forced to play much of last season through the pain barrier, which ultimately caught up with him in the summer after he missed much of Euro 2020 with Gareth Southgate’s England side.
Rashford is likely to miss at least the opening nine games of the campaign, which includes clashes against Leicester and Liverpool as well as the opening trio of Champions League group fixtures.
The England star has been carrying the injury for nine months after tearing a muscle in his left shoulder during a clash against Arsenal in November.
His struggles continued over the course of the season, notching just 11 goals in the league, six short of his tally from the previous campaign.
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Marcus Rashford is out for the first three months of the season (Image: Getty)
After a stunning start to his United career, the last two seasons have been plagued with injuries for Rashford which has not only impacted his form, but could lead to question marks over his long-term future.
The United forward has previously shake off a stress fracture in his back, which would go on to worsen as a double stress fracture, before sustaining ankle ligament damage in March.
Persistent injuries does raise question marks over United’s medical staff, who reportedly informed him his condition would not worsen.
Whether United would be willing to endure a career that is blighted by sporadic spells on the side-lines remains to be seen.
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This injury could have a knock-on effect on the futures of a number of other Man Utd stars, with a number of attackers who were originally set to leave now potentially seeing their future plans changed.
Both Anthony Martial and Daniel James were heading towards the Old Trafford exit door in the aftermath of the arrival of Jadon Sancho.
Martial was linked with a number of Premier League clubs, including Tottenham, but now could see his six-year stay in Manchester continue.
Daniel James struggled to have much of an impact on proceedings last season, playing a predominantly bit-part role off the substitutes bench in Europa League and domestic cup competitions.
This injury to Rashford could present either of James or Martial with the chance to revive their United careers.
Not only in terms of departures, but with so many huge games early on in the campaign, there’s every chance it could temptSolskjaerinto reinforcing his attack by dipping into the transfer market once again.