Arsenal’s second leg clash has already been moved to the Wednesday before due to UEFA rules not allowing two teams to play in the same city on one night.
Chelsea have been given priority because they are FA Cup winners.
"Due to the city clash between Chelsea FC and Arsenal FC, and in order to respect the sporting criteria of the competition (both teams are seeded and have to play the return leg of their respective round of 32 ties at home), one of the two return-leg matches will be played on a Wednesday," a UEFA statement read.
"In accordance with the principles set by the Club Competitions Committee, Chelsea FC have priority, having won the national domestic cup. Arsenal FC with therefore play their return leg in the round of 32 at home on Wednesday 20 February 2019, at 18.00 CET (17.00 GMT), irrespective of their opponents."
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