Conte was the favourite to replace Zinedine Zidane in the summer but turned down the job in favour for some time away from the game.
With no official announcement as of yet, Ramos hinted Loptegui’s end is near.
"I have always said the same, these are not decisions in our hands,” Ramos told reporters.
Real Madrid news: Sergio Ramos has fired a warning to Antonio Conte (Image: GETTY)
Real Madrid news: Ramos has played under Lopetegui with Spain as well as in Madrid (Image: GETTY)
Real Madrid news: Antonio Conte is set to take over at the Santiago Bernabeu (Image: GETTY)
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“We are to the death with the manager who is in place, these decisions come from above, we will see what happens in the next few hours."
The 32-year-old refused to shy away from questions regarding his potential new boss Conte and issued a warning to the Italian.
“Respect is won, it's not imposed. Not one name or another,” he added.
“We have won everything with managers that you know, and at the end, the management of the dressing room is more important than the technical knowledge of a manager."
Real Madrid news: Los Blancos were thrashed 5-1 by Barcelona (Image: GETTY)
Real Madrid have now only won one of their last seven matches in all competitions.
Lopetegui’s tenure has not worked after he departed the Spanish national team in bizarre circumstances on the eve of their World Cup campaign.
Ramos insists he has no problem with the 52-year-old, who has struggled to turn things around.
"I have always had a good relationship with all of the managers and in what I have said to him, I said to him alone. Today there was no moment to speak,” he said.