United are set to play Juventus on Tuesday night in a crunch Champions League tie.
And Mourinho also a clash with City to look forward to before the next international break.
The Portuguese is 5/2 to be the first Premier League manager sacked this season.
But Ladbrokes have Jokanovic in at 11/4 as Fulham’s form takes a nosedive.
Fulham manager Slavisa Jokanovic is 11/4 to be sacked (Image: GETTY)
Mark Hughes is still under pressure at Southampton (Image: GETTY)
Jose Mourinho is also tipped to replace Real Madrid manager Julen Lopetegui (Image: GETTY)
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Jokanovic got Fulham up last season but the Cottages have endured a mixed return to life in the Premier League.
Just one league win all season - coupled with a third straight defeat in Saturday’s 4-2 loss at Fulham - has Jokanovic sweating over his future.
And their downturn has come as Mark Hughes - 6/1 to get the chop - did his chances of remaining the Southampton job a world of good with the 0-0 draw at Bournemouth on Saturday.
Newcastle manager Rafa Benitez is also 6/1 to go first, with the Toon rock bottom of the Premier League table.
Lopetegui has overseen a five-game winless run at Real and the club are supposedly willing to act once Tuesday’s Champions League tie with Plzen is over.
Real could put Santiago Solari in temporary charge until Mourinho is available, although other reports claim Antonio Conte is on Real’s radar.