Middlesbrough FC head coach discusses Man United tactics
Manchester United start with Marcus Rashford up front as leading goalscorer Zlatan Ibrahimovic serves the second of a three-match domestic ban.
And world-record signing Paul Pogba has been replaced by Marouane Fellaini after he picked up a hamstring injury against Rostov on Thursday.
David De Gea returns between the sticks to face Middlesbrough, while Phil Jones, Ashley Young, Michael Carrick and Jesse Lingard also come into the starting XI.
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