“I only have one [centre-back], I would like to have Nemanja Vidic but I only have Nemanja Matic and he’s a midfield player,” he told BT Sport.
“[Chris] Smalling has pain in his foot so he is not available to play, Eric Bailly has a pain in his back.
“Marcos Rojo trained yesterday with the group for the first time after a long absence.
“He’s ready to play and ready to help but not ready to start.
Man Utd news: Mourinho is facing a crisis at centre-back (Image: GETTY)
Man Utd news: Vidic left the club in 2014 (Image: GETTY)
“[Victor] Lindelof has an important injury and the only centre-back we have available to play is Phil [Jones].”
Mourinho insisted that he was not taking Southampton lightly despite the fact they’re in the relegation zone.
“It doesn’t matter [that Southampton are out of form], what matters is the quality,” he added.
“It is a club of great stability, quality of the players, quality of the team, last season they were a little bit in trouble but for many many years they’re a good Premier League team with lots of good players.
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Man Utd news: Herrera bagged the leveller at St Mary's (Image: GETTY)
“I don’t look to the table I look to them.”
United found themselves 2-0 down early on but they managed to fight back through goals from Romelu Lukaku and Ander Herrera.
It was the Belgian’s first goal in 12 appearances.
Marcus Rashford was the provider for both goals as he looks to stamp his mark on the starting line-up.